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Wednesday, July 22, 2020 | History

6 edition of organic chemistry of drug design and drug action found in the catalog.

organic chemistry of drug design and drug action

by Richard B. Silverman

  • 302 Want to read
  • 16 Currently reading

Published by Academic Press in San Diego .
Written in English

    Subjects:
  • Pharmaceutical chemistry.,
  • Bioorganic chemistry.,
  • Molecular pharmacology.,
  • Drugs -- Design.,
  • Chemistry, Organic.,
  • Chemistry, Pharmaceutical.,
  • Drug Design.,
  • Pharmacokinetics.

  • Edition Notes

    Includes bibliographical references and index.

    StatementRichard B. Silverman.
    Classifications
    LC ClassificationsRS403 .S55 1992
    The Physical Object
    Paginationxiv, 422 p. :
    Number of Pages422
    ID Numbers
    Open LibraryOL1565259M
    ISBN 100126437300
    LC Control Number91047041

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Organic chemistry of drug design and drug action by Richard B. Silverman Download PDF EPUB FB2

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This new edition includes Cited by: The Organic Chemistry of Drug Design and Drug Action Paperback – January 2, by Richard B. Silverman (Author)/5(17). The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules.

A medicinal chemist tinkers the drug design parameters to augment the potency, selectivity, and duration of the drug's action and to reduce the toxicity of the drug.

The concept of quantitative drug design is based on the fact that the biological properties of a compound are a function of its physicochemical parameters.

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules.

This new edition. "The Organic Chemistry of Drug Design and Drug Action" offers valuable and in-depth suggestions concerning many facets of drug discovery. Moreover, this volume is worthwhile reading for the several detailed chapters of historical interest that it contains, although this material is still placed in context with the biochemical principles.

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n Emphasizes the use of the principles of physical organic chemistry as a basis for drug design n Discusses organic reaction mechanisms of clinically important drugs with mechanistic schemes n Uses figures and literature references extensively throughout n This text is not merely a "compilation of drugs and uses," but features selected drugs as examples of Book Edition: 1.

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules.

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TY - BOOK. T1 - The Organic Chemistry of Drug Design and Drug Action. AU - Silverman, Richard B. PY - Y1 - M3 - Book. BT - The Organic Chemistry of Drug Design and Drug Action. PB - Elsevier/Academic Press. CY - San Diego. ER -Cited by:   The Organic Chemistry of Drug Design and Drug Action by Richard B.

Silverman,available at Book Depository with free delivery worldwide.4/5(56). This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules.

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The Organic Chemistry of Drug Design and Drug Action Second Edition Richard B. Silyerman Northwestern University Department of Chemistry Evanston, Illinois ELSEVIER ACADEMIC PRESS Amsterdam • Boston • Heidelberg • London • New York • Oxford Paris • San Diego • San Francisco • Singapore • Sydney • Tokyo.

Book Review: The Organic Chemistry of Drug Design and Drug Action. By R. Silverman. James B. Doherty. Merck & Co. Inc., Rahway NJ (USA) Search for more papers by this author. James B. Doherty. Merck & Co. Inc., Rahway NJ (USA) Search for more papers by this author.

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By R. B. Silverman. James B. Doherty. Merck & Co. Inc., Rahway NJ (USA)and you may need to create a new Wiley Online Library account. Request Username.

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